How to control miRNA maturation?

Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R

RNA Biol 2009 Nov-Dec;6(5):536-40

Abstract

PMID: 19875945

In this point of view we discuss the role of co-activators and co-repressors of miRNA precursors maturation, the possibility that their functions are post translationally regulated by different signaling pathways, and their potential role in the miRNA-dependent control of cell proliferation and differentiation.