“ Multiple levels of transcriptome regulation “
Thursday, April 2 at 4pm in Rampal amphitheater (main hall C3M)
16:00 – 17:00 “Studying the dynamics of RNA metabolism through the profiling of total and nascent RNA.” by Mattia Pelizzola from the Istituto Italiano di Tecnologia Center for Genomic Science, Milan, Italy
17:00 – 17:30 “Metabolic and functional diversity of macrophages ” by Stoyan Ivanov from the C3M
from 17:30 lite bites and beer
Mattia Palizzola is the invited spekear ( url: http://genomics.iit.it/research/epigenomics-and-transcriptional-regulation )
His presentation will be about the abundance and responsiveness to modulations of premature and mature RNA species are set by the combined action of three key steps: premature RNA synthesis, processing of premature into mature RNA, and degradation of the latter. These steps are governed by corresponding kinetic rates, which collectively determine the RNA dynamics of transcripts. I will illustrate how RNA-seq data can be used for the genome-wide gene-level quantification of RNA dynamics, and how these data are advancing our understanding of the transcriptional programs driven by the MYC oncogene.