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CHIRGEN:
Chiralité et Gènes
CHIRGEN: Chirality of
Genes
Project ANR-12-IS07-0006
C001-Conacyt-ANR-188689
Duration 2013-2015
Coordinator (France):
Prof. Dr. U. Meierhenrich
Partner: Dr. L.
d'Hendecourt
Partner: Dr. L. Nahon
Coordinator (Mexico):
Prof. Dr. T. Buhse
Tel : +33 (0)4 92 07 61 77
Fax :+33 (0)4
92 07 61 51
Uwe.Meierhenrich@unice.fr
Objective
The bilateral CHIRGEN-project
proposes to discover the
origin of the genetic
asymmetry as the initial and
crucial step toward the origin
of life by utilizing both
interstellar asymmetric
photochemcial processes
(France) and autocatalytic
amplification (Mexico).
Le projet
bilatéral CHIRGEN propose de
découvrir l'origine de
l'asymétrie du code
génétique comme un moyen de
franchir une étape cruciale
vers la compréhension de
l'origine de la vie en
utilisant à la fois un
scenario astrophysique
proposant une photochimie
asymétrique à partir de
lumière cpl (France) puis
d'une amplification
autocatalytique (Mexique).
Conference
Organizations
Organization of the 3rd
European GCxGC Congress at the
University Nice Sophia
Antipolis, 17-18 September
2013, Nice, France.
Organization of the
Rosetta-COSAC General Meeting
at the University of Nice
Sophia Antipolis, 27-28
January 2014, Nice, France.
Links
to Chirgen
Official ANR website (link)
Portail Franco-Mexicain (link)
Official Conacyt website (link)
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Selected CHIRGEN Publications
Meinert C.,
Myrgorodska I., de Marcellus P., Buhse
T., Nahon L., Hoffmann S.V.,
d'Hendecourt L., Meierhenrich U.J.:
Ribose and related sugars from
ultraviolet irradiation of
interstellar ice analogs. Science
352 2016, 208-212. 
Goesmann F., Meierhenrich U.J. et al.:
Organic compounds on comet
67P/Churyumov-Gerasimenko revealed by
COSAC mass spectrometry. Science
349 2015, 497.
De Marcellus P., Meinert C.,
Myrgorodska I., Nahon L., Buhse, T.,
Le Sergeant d'Hendecourt L.,
Meierhenrich U.J.: Aldehydes and
sugars from evolved precometary ice
analogs: Importance of ices in
astrochemical and prebiotic evolution.
Proc. Natl. Acad. Sci. USA 112
2015, 965-970
Myrgorodska I., Meinert C., Martins
Z., Le Sergeant d'Hendecourt L.,
Meierhenrich U.J.: Molecular chirality
in meteorites and interstellar ices,
and the chirality experiment on board
the ESA cometary Rosetta mission. Angew.
Chem. Int. Ed. 54 2015,
1402-1412
Meierhenrich UJ:
Comets and Their Origin.
Wiley, Weinheim 2015
Meinert C, Hoffmann SV, Cassam- Chenaï
P, Evans AC, Giri C, Nahon L,
Meierhenrich UJ: Photonenergy-
controlled symmetry breaking with
circularly polarized light. Angewandte
Chemie
International Edition, 53 2014,
210-214
Bredehöft JH, Jones NC, Meinert C,
Evans AC, Hoffmann SV, Meierhenrich
UJ: Understanding Photochirogenesis:
Solvent Effects on Circular Dichroism
and Anisotropy Spectroscopy. Chirality
26 2014,
373-378
Meinert C, Meierhenrich UJ:
Derivatization and Multidimensional
Gas-Chromatographic Resolution of
alpha-Alkyl and alpha-Dialkyl Amino
Acid Enantiomers. ChemPlusChem
79 2014,
781-785
Meierhenrich UJ, Cason JRL, Szopa C,
Sternberg R, Raulin F, Thiemann WH-P,
Goesmann F: Evaluating the robustness
of the enantioselective stationary
phases on the Rosetta mission against
space vacuum vaporization. Advances
in Space Research, 52 2013,
2080-2084
Evans AC, Meinert C, Bredehöft JH,
Giri C, Jones NC, Hoffmann SV,
Meierhenrich UJ: Anisotropy Spectra
for Enantiomeric Differentiation of
Biomolecular Building Blocks, Topics
in Current Chemistry, 341 2013,
271-300
Keywords:
- Amino acid
- Chirality
- Origin of Life
- Parity
- Photochemistry
- Prebiotic chemistry
- Rosetta Mission
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